Ionizable lipid nanoparticles (LNPs) have gained attention as mRNA delivery platforms for vaccination against COVID-19 and for protein replacement therapies.LNPs enhance mRNA stability, circulation time, cellular uptake, and preferential delivery to specific tissues compared to mRNA with no copyright platform.However, LNPs are only in the beginning
We Hairball Remedy present the measurement principle and the optical design of a Quad Mach Zehnder (QMZ) interferometer as HSRL technique, allowing simultaneous measurements of particle backscattering and wind velocity.Key features of this concept is to operate with a multimodal laser and do not require any frequency stabilization.These features ar
Understanding how initial radiation injury translates into long-term effects is an important problem in radiation biology.Here, we define a set of changes in the transcription profile that are associated with the long-term response to radiation exposure.The study was performed in vivo using zebrafish, an established radiobiological model organism.T
Testicular (germ cell) cancer is a model of Circulation Pump a chemocurable malignancy and tends to have a favourable prognosis even in advanced stages due to exquisite sensitivity to platinum-based chemotherapy.However, both acute and longer-term toxicities of multiagent chemotherapy remain significant as causes of morbidity, very occasionally mor
Pyoderma gangrenosum is often associated with a systemic disease.copyright-induced pyoderma gangrenosum, most probably caused by levamisole, has been described recently and typically presents as multiple, large cribriform ulcers.Peri-nuclear antineutrophil cytoplasmic antibody is Safety Wellingtons the most common serological finding.A strong couns